Some actors, no matter how long their career or how great their talent, will forever be first known for one iconic TV role. This isn’t an indictment of their careers at all. In fact, in many ways, it tells the whole story. They were so good at one particular role that no matter what, that’s what people will think of first. To be sure, these are some of the best actors of their generations ,and they deserve praise for all their roles, but especially these.
Kelsey Grammer – Frasier Crane
For a total of an amazing 20 years, Kelsey Grammer has played Frasier Crane. First on Cheers, then on its spinoff Frasier, and again in the reboot of Frasier in the 2020s. There may be no more obvious actor to include on this list.
Mariska Hargitay – Olivia Benson
Mariska Hargitay is Hollywood royalty as the daughter of Jayne Mansfield, and she’s carved out on heck out her own career playing Olivia Benson on NBC’s Law & Order: Special Victims Unit. She has played since the end of the 20th Century, more than 25 seasons in total. There is no other character in prime time history with a longer run than Hargitay’s Benson. It’s remarkable.
Arrested Development. She was so hilarious and quotable that it’s easy to see why this is the case.
Peter Falk – Columbo
Peter Falk completely embodied Detective Columbo on the show that carried that character’s name. He defined a new kind of TV detective, a style that has been often imitated but never duplicated over the years since Columbo debuted. He was funny and wicked smart. A Holmesian-style detective who never found a dry cleaner.
Tom Selleck – Thomas Magnum
Tom Selleck was a hard one to include here. Thomas Magnum was one of two iconic roles, along with Frank Reagan on Blue Bloods, that Selleck has played in his career. That’s not to mention Jesse Stone, another fan-favorite. But in the end, it’s all about Magnum P.I., one of the best shows ever.
Lauren Graham – Lorelai Gilmore
Lauren Graham is another tough one here, because Lorelai Gilmore is hardly her only big role on TV, but none of her other shows have been nearly as enduring as Gilmore Girls and that isn’t likely to change in the future. It’ll always be what her fans think of first.
Lucille Ball – Lucy Ricardo
Lucille Ball was a groundbreaking legend, and that is entirely due to her iconic character Lucy Ricardo on I Love Lucy. The list of what made the show, and the comedic actor, is so long, we could never fill it out here, but she also doesn’t really need any explanation. She’s the queen of early TV for very good reason, and that can never be taken away.
Peter Dinklage – Tyrion Lannister
Peter Dinklage might not like to hear this… or maybe he would… but Tyrion Lannister is such an amazing role, and Dinklage’s performance is completely worthy of such an iconic literary and TV character. Game of Thrones took over the television watching audience completely, and Dinklage’s Lannister was almost everyone’s favorite. He’s done great work all through his long career, but it will be impossible to top Tyrion.
Sean Hayes – Jack McFarland
Jack McFarland from Will & Grace is one of the most underappreciated characters in any sitcom in Hollywood history. Sean Hayes is fantastic in the role, and he’ll have people saying “Just Jack!” forever.
Angela Lansbury – Jessica Fletcher
Angela Lansbury had a storied career that lasted decades, and every time she appeared on screen, she lit it up. Jessica Fletcher on Murder She Wrote was her crowning achievement. She’s one of the best TV detectives of all time, even if there were way too many murders in Cabot Cove than there should have been.
Henry Winkler – The Fonz
Arthur Herbert Fonzarelli. Fonzie. The Fonz. A character of many names, and one iconic look. Henry Winkler has had a career that most actors can only dream of, but his role on Happy Days will always be what he is first known for. We should all be so cool.
Sarah Michelle Gellar – Buffy Summers
Sarah Michelle Gellar’s role in the movie Cruel Intentions may be her most iconic movie role, but it doesn’t eclipse her role as Buffy Summers on Buffy the Vampire Slayer. Not even close. It’ll always be her most beloved role.
James Gandolfini – Tony Soprano
On one hand, it’s a shame that James Gandolfini is on this list. His premature death will always have us asking “what if?” On the other hand, he is so freaking GREAT as Tony Soprano in The Sopranos, that its impossible not to include him here. Just watching him in anything else, or old interviews, you quickly realize that he completely disappeared into the gangster. It’s remarkable.
Gillian Anderson – Dana Scully
Speaking from experience, I can say that many teenagers in the 1990s have a huge crush on Dana Scully on The X-Files. She was smart and capable, but with an air of mystery that really kept viewers guessing, in the best way.
William Shatner – Captain Kirk
Personally, I think William Shatner’s best role was on Boston Legal. He was also amaing in TJ Hooker. However, even if he had 1000 legendary roles over his career, he would still be most remember for James T. Kirk in Str Trek. That’s how iconic the role, and the show are.
Matthew Perry – Chandler Bing
It was a real tragedy when the world lost Matthew Perry in late 2023. He was a once-in-a-generation talent and, in many ways, was first among equals on Friends. He was in some other great projects, like The Whole Nine Yards and Fools Rush In, but let’s be honest, he’ll always be Chandler in our hearts.
Amy Poehler – Leslie Knope
Amy Poehler was a star on SNL and in a ton of great movies. However, she was absolutely born to play Leslie Knope on Parks & Rec. It’s almost hard to believe she isn’t actually Leslie in real life, and that’s meant to be the most sincere of compliments.
Michael K. Williams – Omar Little
Of all the amazing characters and actors on The Wire, Omar and Michael K. Williams stand out above them all. He was one of the most honest and complex characters in TV history, and the late Williams, another actor we lost way too soon, will be forever remembered for his portrayal of the Baltimore stick-up man.
George Wendt – Norm Peterson
Cheers had an amazing ensemble of comedic actors, and as a kid, my favorite was always George Wendt and his character Norm. He was the most popular guy in the bar and the most popular with viewers. When Wendt died in 2025, everyone started sharing their favorite moments of his from the show, despite the show ending decades ago.
Mary Tyler Moore – Mary Richards
Mary Tyler Moore made it after all, and all on her own. Her titular show was the highlight of her long, incredible career, and it’s a good thing the show was named after her, because she deserves to be remembered forever for it.
Caroll O’Connor – Archie Bunker
Caroll O’Connor’s role as Archie Bunker became one of the most iconic and most important in television history. The groundbreaking sitcom, All In The Family, changed TV forever, and Bunker, with his bigotry and chauvinism, reinvented just how much a simple sitcom could say about society.
Rainn Wilson – Dwight Schrute
Of all the characters on The Office, Dwight, played by Rainn Wilson, was the one we all loved to hate the most. It must have been such a fun role for Wilson, because he never phoned it in, and he never let us down; we could count on him driving us nuts every week. I mean that in the very best way.
Wayne Knight – Newman
Wayne Knight has popped up in all kinds of roles in his career. We’ll never forget him for his performance in the original Jurassic Park, for example, but it’s Newman on Seinfeld that we’ll always love him most for. He might not have been a main character, but that is testimony to just how good he was. He’s as remembered as the “big four” despite playing a much more limited role. That takes a great actor and an even better performance, and he did over the entire run of the show.
Ian McShane – Al Swearengen
Al Swearengen from Deadwood is one of the best characters of the prestige era of TV. Ian McShane has had a long, distinguished career, and at the top of the list of his great performances is as the foul-mouthed, tavern-owning gangster in the HBO Western.
Danica McKellar – Winnie Cooper
Ask anyone in Gen X about Danica McKellar, and they might mention her Hallmark movies. They might also mention her wonderful guest turn on The West Wing. In the case of both of those, though, they will come after they fondly reminisce about watching her as Winnie Cooper on The Wonder Years. They grew up with Winnie and Kevin (Fred Savage). It was her earliest role, but it remains her most iconic.